Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
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Author/sAbellán Ruiz, María Salud; Barnuevo Espinosa, María Dolores; Contreras, Carlos; Luque, Antonio; Sánchez, Francisca; [et al.]
Discipline/sCiencias de la Alimentación
Subject/sColonic transit time
Soluble dietary fibre
PURPOSE: Increased awareness of the importance of dietary fibre has led to increased interest in "functional" fibre components like digestion-resistant maltodextrin (RMD). This randomized, placebo-controlled, double-blind study assessed the effects of RMD in the colonic transit time (CTT) and defecation characteristics (frequency, stool volume and consistency). METHODS: Sixty-six healthy adult volunteers (32 men) who did not have a daily defecation habit had a 7-day run-in period before the 21-day intervention period with RMD or placebo. CTT and segmental CTT (SCTT) were assessed by a single abdominal X-ray film taken at the end of both periods after radiopaque marker ingestion. Defecation characteristics and intestinal functions were also assessed, which were self-reported by patients. Intragroup comparisons were evaluated by Student's paired t test, Bonferroni test and Chi-square test, while time comparisons by analysis of variance (ANOVA) and time-by-treatment interaction by re...